Is Gout Caused Due To Genetic Predisposition?


Gout is a variant of inflammatory arthritis, and it is known for its severely painful attacks. It has been referred to as “the disease of kings” because it commonly develops in those who drink excessively and eat meat. Also, the underlying cause for this condition is the build-up of uric acid in the blood, which deposits as urate crystals in the joints, especially the one above the toe. Many researchers believe that there is a hereditary aspect to gout, and the purpose of this article is to investigate this topic.

Understanding Gout

As already stated in the introduction, gout is caused due to the build-up of uric acid, i.e., hyperuricemia. Remember that uric acid is produced as a by-product of metabolism, and it is eliminated out of the body through urine. The excess uric acid deposits as sharp needle-like crystals; they can cause severe pain, swelling, tenderness of the affected joint, and redness.

The level of uric acid increases above normal levels due to multiple reasons. Firstly, its levels in the blood rise beyond the normal level due to metabolic issues and this puts stress on the kidneys. Secondly, eating excess amounts of certain types of food like red meat, organ meat, pulses, and seafood can make the body produce more uric acid. Some people ask the question “is gout hereditary?” and the answer to that is it develops due to a mix of genetic and as well as environmental elements.

The Risk For Developing Gout

There are a couple of factors that elevate your risk of falling prey to gout. New research suggests that the link between gout and genetics is stronger than it was believed; in fact, it has more impact than the diet.

Latest Inquests On Gout

In 2018 a meta-analysis was conducted to find the kinship between genetics and eating habits. From this, it was found that the risk of developing gout due to genetic predisposition was greater than that of diet. Apart from this, according to researchers, the risk of developing gout from eating foods like red meat, beer, and a certain type of seafood is less than 1%.

Importance Of Healthy Lifestyle On Gout

Listed below are tips for leading a healthy lifestyle to reduce the risk of developing gout:

  • Maintain a healthy weight
  • Drink adequate amounts of water, i.e., keep yourself hydrated

On a final note, talk with your doctor and do regular check-ups if you have a family history of gout.